Estimated read time: 5-6 minutes
This archived news story is available only for your personal, non-commercial use. Information in the story may be outdated or superseded by additional information. Reading or replaying the story in its archived form does not constitute a republication of the story.
[STK]
[IN] HEA FOD
[SU]
-- WITH PHOTO -- TO FOOD, HEALTH, AND NATIONAL EDITORS:
Study Finds Sucralose, Sweetening Ingredient in SPLENDA@ Sweetener
Products, Has Same Effect As Water On The Body
FT. WASHINGTON, Pa., March 18, 2014 /PRNewswire-USNewswire/ --
Consuming sucralose in a drink is shown to have the same effect as
water on a person's sugar and insulin levels, according to a study
reported in Diabetes Care, a journal of the American Diabetes
Association(1). Sucralose is the no calorie sweetening ingredient in
SPLENDA@ Sweetener Products.
The study was led by Tongzhi Wu, MD, PhD, at the University of
Adelaide School of Medicine, and funded by the National Health and
Medical Research Council in Australia. The results showed that neither
sucralose alone, or when combined with another no calorie sweetener,
acesulfame potassium (AceK), had any effect on insulin secretion or
blood sugar.
In the study, Wu and his team followed ten healthy men who drank four
different drinks on four different occasions after an overnight fast.
The four drinks were water; water with sucralose; water with AceK; and
water with both sucralose and AceK. Ten minutes later each one drank
a sugar solution.
The participant's sugar, insulin, and GLP-1 blood levels were measured
before, and for six hours after, drinking the sugar solution. (GLP-1
is a hormone known to slow gastric emptying and has a role in appetite
regulation.) The results showed no differences in outcomes for any of
these measures, whether the men drank plain water, or water sweetened
with either or both sweeteners. It should be noted that using all men
in such a study is a way to minimize the possibility of effects
unrelated to testing. For example, hormonal changes that can occur
with menstruation can influence insulin levels(2,3).
"Our findings are . consistent with previous reports." the authors
state, and they concluded that ". sucralose and AceK, either alone or
in combination, have no acute effect on gastric emptying, GLP-1, or
glycemic responses after oral glucose in healthy humans."
In their comments in Diabetes Care(1), Dr. Wu and colleagues point out
that a previous study reported that drinking diet soda increased GLP-1
levels. This result was further interpreted to mean that the
artificial sweeteners could potentially impact metabolism and increase
a person's sugar levels.
In contrast, Dr. Wu noted that, "The design of that study was,
however, suboptimal, as the diet soda contained a number of substances
(including caramel color, gum acacia, natural flavors, citric acid,
potassium benzoate, phosphoric acid, and potassium citrate) that were
not controlled for." Consequently, Dr. Wu and his team chose to give
participants in their study sweeteners in water to avoid the potential
effect of these other substances on glucose, insulin or GLP-1.
"The Wu study provides more evidence that SPLENDA@ can be used safely
by everyone, including pregnant women, children and people with
diabetes," says Maureen Conway, R.D., Director of Nutritional Affairs
for McNeil Nutritionals, LLC. "This is especially meaningful for
people with diabetes and their caregivers. Foods and beverages
sweetened with SPLENDA@ No Calorie Sweetener can be a great way for
people to enjoy the foods they love as part of their diabetes meal
plan. And using SPLENDA@ with regular physical activity can be an
excellent way to help with weight management."
Sucralose, the no calorie ingredient in SPLENDA@ Sweetener Products,
is not sugar and the body does not recognize it as such. Unlike sugar,
sucralose is not broken down for energy. It is not a source of
carbohydrate or glucose, and clinical studies have shown it has no
effect on blood glucose levels, insulin secretion or blood levels,
glycosylated hemoglobin levels (HbA1c), or blood glucose control.
SPLENDA@ Sweetener Products have been used safely by millions of
people around the world for more than 20 years, supported by research
data from more than 110 studies. Both the American Diabetes
Association (ADA) and the Academy of Nutrition and Dietetics (AND)
support the use of low calorie sweeteners such as sucralose as a
useful tool in managing weight and diabetes. For more information,
visit www.splenda.com or www.foodinsight.org.
(1) Wu T, Bound MJ, Standfield SD, Bellon M, Young RL, Jones KL,
Horowitz M, Rayner CK. Artificial sweeteners have no effect on
gastric emptying, glucagon-like peptide-1, or glycemia after oral
glucose in healthy humans. Diabetes Care, 2013. 36: e202-e203.
(Available at:
http://care.diabetesjournals.org/content/36/12/e202.full)
(2) Brennan IM, Feltrin KL, Nair NS, Hausken T, Little TJ, Gentilcore
D, Wishart JM, Jones KL, Horowitz M, Feinle-Bisset C. Effects of the
phases of the menstrual cycle on gastric emptying, glycemia, plasma
GLP-1 and insulin, and energy intake in healthy lean women. Am J
Physiol Gastrointest Liver Physiol. 2009. 297:G602-610. (Available
at: http://www.ncbi.nlm.nih.gov/pubmed/19556358)
(3) Schisterman EF, Mumford SL, Sjaarda LA. Failure to consider the
menstrual cycle phase may cause misinterpretation of clinical and
research findings of cardiometabolic biomarkers in premenopausal
women. Epidemiol Rev. 2014. 36:71-82. (Available at:
http://www.ncbi.nlm.nih.gov/pubmed/24042431)
Logo - http://photos.prnewswire.com/prnh/20140318/DC84622LOGO
SOURCE SPLENDA
-0- 03/18/2014
/CONTACT: Peggy Ballman, McNeil Nutritionals, LLC, 908-310-7721, pballman@its.jnj.com
/Photo: http://photos.prnewswire.com/prnh/20140318/DC84622LOGO
AP PhotoExpress Network: ADD PRN#
PRN Photo Desk, photodesk@prnewswire.com
CO: SPLENDA
ST: Pennsylvania
IN: HEA FOD
PRN
-- DC84622 --
0000 03/18/2014 13:47:00 EDT http://www.prnewswire.com
Copyright © The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
