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Twice the speed limit...No sign of Marine helicopter...Siege in Kabul

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PHILADELPHIA (AP) — Preliminary data show that the Amtrak train that derailed in Philadelphia last night was going around 106 mph in a curve that had a posted 50 mph speed limit. The train's operator is said to have fully applied the emergency brakes, which only slowed the train slightly. At least seven people were killed. An official with the National Transportation Safety Board says he suspects investigators will be on the scene of a deadly Philadelphia train derailment for about a week.

KATHMANDU, Nepal (AP) — Officials in Nepal say there's still no sign of a U.S. Marine Corp helicopter that was reported missing on Tuesday while it was delivering aid to earthquake victims. Eight people were aboard, including six Marines. Tuesday's quake killed at least 79 people and injured more than 2,300. A quake less than three weeks ago killed more than 8,000.

KABUL, Afghanistan (AP) — An eyewitness says several dozen people, including foreigners and Americans, are likely being held at a besieged guesthouse in Kabul, Afghanistan. Gunmen stormed the Park Palace Hotel late Wednesday. No one has claimed responsibility for the attack, though the Taliban have attacked guesthouses before in Kabul.

WASHINGTON (AP) — The government will soon require labels on packages of beef tenderized by machines so shoppers know to cook it thoroughly. The Agriculture Department says the labels will be required starting in May 2016. Mechanically tenderized meat is poked with needles or blades to make it tender, a process that can transfer bacteria from the outside of the cut of beef to the inside.

UNDATED (AP) — A large study suggests that a vitamin might modestly lower the risk of the most common types of skin cancer in people with a history of these relatively harmless but troublesome growths. Researchers in Australia found that people who took nicotinamide (nih-kuh-TEE'-nuh-myd), a form of vitamin B3, for a year had a 23 percent lower rate of new skin cancers compared to others who took dummy pills.

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