DURHAM, N.C., Sep 22, 2004 (United Press International via COMTEX) -- A Duke University study suggests anger and hostility in healthy people can produce high levels of a substance that promotes heart disease and stroke.
Researchers at Duke's Medical Center in Durham, N.C., also included moderate depressive symptoms in their study of healthy people prone to such problems.
They said such problems produce a substance called C-reactive protein or CRP.
The researchers said CRP has garnered considerable attention for its role in both promoting and predicting cardiovascular disease and stroke in initially healthy people.
It is produced by the liver in response to inflammation, and inflammation has recently been shown to underlie the plaque that forms inside arteries as they clog.
The Duke study is the first to link this combination of negative psychological attributes with higher levels of CRP in people without traditional risk factors for heart disease, said Edward Suarez, lead author of the study.
Results of the study are published in the September issue of the journal Psychosomatic Medicine.
Copyright 2004 by United Press International.