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Cyclenium Pharma and Southern Research Institute Announce Drug Discovery and Development Collaboration


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[STK]

[IN] PHA

[SU] SVY TRI NPT

TO MEDICAL, NATIONAL, AND SCIENCE EDITORS:

Cyclenium Pharma and Southern Research Institute Announce Drug

Discovery and Development Collaboration

SHERBROOKE, Quebec and BIRMINGHAM, Ala., April 17, 2014

/PRNewswire-USNewswire/ -- Cyclenium Pharma Inc., an emerging

pharmaceutical company specializing in the research and development of

novel drug candidates based on proprietary macrocyclic chemistry,

today announced the signing of a discovery and co-development

agreement with Southern Research Institute, a not-for-profit 501(c)(3)

scientific research organization founded in 1941. The collaboration

will utilize Cyclenium's proprietary libraries of next generation

macrocyclic molecules and associated hit-to-lead optimization

expertise in combination with Southern Research's extensive

capabilities in target screening, compound profiling and preclinical

development. The goal is to discover and jointly develop new clinical

candidates for the treatment of cancer, infectious diseases and

neurological conditions.

"We are very pleased to have initiated this collaboration with a

prestigious organization like Southern Research," stated Helmut

Thomas, Ph.D., President & CEO of Cyclenium. "Their breadth of

expertise and long history of successful contributions to drug

discovery and development will provide strong synergy for our

proprietary macrocyclic technology with the expectation of multiple

novel candidates resulting from our joint efforts over the next few

years."

"Cyclenium's proprietary macrocyclic libraries are well suited for use

against many of the challenging targets we are currently working on,"

stated Mark J. Suto, Ph.D. Vice-President Drug Discovery Division

Southern Research Institute. "For example, screening of currently

available small molecule libraries has not been very successful in the

identification of new antibiotics and in targets associated with

disrupting protein-protein interactions. The Cyclenium macrocycle

libraries are unique in that they combine the complexities found in

natural products with the drug-like properties needed for successful

drug discovery. We are looking forward to collaborating with Cyclenium

in the identification of new therapeutics."

About Cyclenium Pharma Cyclenium Pharma is an emerging pharmaceutical

research and development company pursuing development of selected

product opportunities in areas of unsatisfied medical need, while

simultaneously creating a second generation macrocyclic drug discovery

technology. Cyclenium is building value through progression of

internal programs and establishing collaborations with innovative

pharmaceutical and biotechnology companies seeking to modulate

difficult disease targets. For more on Cyclenium Pharma, please see:

www.cyclenium.com.

About Southern Research Institute Southern Research Institute is a

not-for-profit 501(c)(3) scientific research organization founded in

1941 that conducts preclinical drug discovery and development,

advanced engineering research in materials, systems development, and

environment and energy research. Approximately 500 scientific and

engineering team members support clients and partners in the

pharmaceutical, biotechnology, defense, aerospace, environmental and

energy industries. From discovery to clinical trials, Southern

Research contributes to the search for new and better drugs and

vaccines through a comprehensive continuum of capabilities. As a

contract research organization, Southern Research provides preclinical

drug development and clinical trial support services to pharmaceutical

and biotechnology companies on an outsourced basis. Southern Research

is headquartered in Birmingham, AL, with additional laboratories and

offices in Wilsonville and Huntsville, AL, Frederick, MD, Durham, NC,

Houston, TX, and Cartersville, GA. For more information visit:

http://www.southernresearch.org.

Contacts: Helmut Thomas, Ph.D. President & CEO Cyclenium Pharma Inc.

Telephone: + 1 514-745-1439 hthomas@cyclenium.com

Mark J. Suto, Ph.D Vice President Drug Discovery Division Southern

Research Institute Telephone: +1 205-581-2522

suto@southernresearch.org

SOURCE Southern Research Institute

-0- 04/17/2014

/Web Site: http://www.southernresearch.org

CO: Southern Research Institute

ST: Quebec Alabama

IN: PHA

SU: SVY TRI NPT

PRN

-- DC07985 --

0000 04/17/2014 18:00:00 EDT http://www.prnewswire.com

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